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Related Concept Videos

Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Homeostatic Imbalances in Body Temperature01:19

Homeostatic Imbalances in Body Temperature

Hyperthermia occurs when the body's temperature becomes unusually high, often due to heat exposure, intense physical activity, or certain illnesses. This condition can create a dangerous cycle where elevated body temperature increases the metabolic rate, generating more heat and potentially leading to organ failure and brain damage. A severe form of hyperthermia, called heat stroke, can raise body temperature to life-threatening levels. Fever, on the other hand, is a controlled form of...
Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Hypoglycemia and Glucagon01:15

Hypoglycemia and Glucagon

Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...

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Related Experiment Video

Updated: May 21, 2026

Protocol for Long Duration Whole Body Hyperthermia in Mice
07:56

Protocol for Long Duration Whole Body Hyperthermia in Mice

Published on: August 25, 2012

Emergency preparedness case study: malignant hyperthermia.

Darlene Hutton1

  • 1dhutton@bellnet.com

Plastic Surgical Nursing : Official Journal of the American Society of Plastic and Reconstructive Surgical Nurses
|June 1, 2012
PubMed
Summary
This summary is machine-generated.

Malignant hyperthermia (MH) is a rare but dangerous inherited syndrome during anesthesia. Prompt recognition and treatment drastically reduce MH mortality from 80% to 5%.

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Last Updated: May 21, 2026

Protocol for Long Duration Whole Body Hyperthermia in Mice
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Published on: August 25, 2012

A Preclinical Model of Exertional Heat Stroke in Mice
08:22

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Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model
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Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

Area of Science:

  • Anesthesiology
  • Medical Genetics

Background:

  • Malignant hyperthermia (MH) is a rare, inherited hypermetabolic crisis.
  • It occurs in 1:50,000 adults and 1:15,000 pediatric patients during anesthesia.
  • MH carries a high mortality rate if not recognized and treated promptly.

Observation:

  • This case study presents a scenario of malignant hyperthermia.
  • It highlights the critical importance of early diagnosis in surgical settings.
  • The case prompts review of risk factors, clinical signs, and symptoms.

Findings:

  • Untreated MH mortality can reach 80%.
  • With prompt intervention, mortality is reduced to 5%.
  • Key aspects include risk assessment and recognizing MH signs.

Implications:

  • Early recognition and rapid treatment are crucial for patient survival.
  • Understanding MH pathophysiology aids in risk assessment and management.
  • Nursing responsibilities are vital in managing this anesthetic emergency.