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Updated: May 21, 2026
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Predicting Gene Silencing Through the Spatiotemporal Control of siRNA Release from Photo-responsive Polymeric Nanocarriers
Published on: July 21, 2017
Near-infrared light-responsive intracellular drug and siRNA release using au nanoensembles with
Yi-Ting Chang1, Pei-Yi Liao, Hwo-Shuenn Sheu
1Department of Chemistry and Center for Micro/Nano Science and Technology, National Cheng Kung University, Tainan, 701 Taiwan.
Advanced Materials (Deerfield Beach, Fla.)
|June 1, 2012
Abstract:
Taking advantage of the character of Au nanorods (NRs) to absorb NIR light, a NIR-responsive oligonucleotide-gated ensemble is developed to perform intracellular drug delivery. Using an oligonucleotide bio-gate enables siRNA release into cells for translational regulation as well as cytotoxicity in anti-cancer drug delivery.
