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Updated: May 21, 2026

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
Published on: November 10, 2017
Microwave-assisted seeded growth of lanthanide-based nanoparticles for imaging and therapy
Florian Mayer1, Joop A Peters, Kristina Djanashvili
1Department of Biotechnology, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands.
Abstract:
Size control: Particles designed for imaging and therapy need to be size tunable to ensure their optimal performance. A highly reproducible procedure for the preparation of uniform, spherical, lanthanide-based nanoparticles (NPs) was developed. The size of the particles can be predefined to an accuracy of up to a few nanometers by microwave-generated temperature control and the choice of aging time (see figure).
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