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Published on: June 17, 2019
Multiclonal origin of macrolide-resistant Mycoplasma pneumoniae isolates as determined by multilocus variable-number
Yang Liu1, Xinye Ye, Hong Zhang
1Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
Abstract:
There was a high percentage of macrolide resistance in Mycoplasma pneumoniae clinical isolates in China. The genetic relatedness of macrolide-resistant M. pneunomiae strains was investigated using the multilocus variable-number tandem-repeat assay (MLVA). Among 152 M. pneunomiae isolates, the 137 macrolide-resistant strains were clustered into 15 MLVA types, indicating that the high macrolide resistance rate in M. pneumoniae is a result of the dissemination of the multiple resistant clones.
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