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Updated: May 21, 2026
Measuring Psoriasis Severity at Home
Published on: March 1, 2024
Evaluation of clinical and ultrasonographic parameters in psoriatic arthritis patients treated with adalimumab: a
M Teoli1, A Zangrilli, M S Chimenti
1Department of Dermatology, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy. miriam teoli@libero.it
Objectives:
The aim of this study was to evaluate clinical and US-PD parameters in PsA during adalimumab treatment.
Methods:
A retrospective study has been conducted in forty patients affected by moderate-to-severe peripheral PsA. Clinical, laboratory, and US-PD evaluations were performed at baseline, after 4, 12, and 24 weeks of treatment. They included erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), visual analogue scale (VAS), Health Assessment Questionnaire (HAQ) modified for Spondyloarthritis, Psoriasis Area Severity Index (PASI) score, the 28-joint Disease Activity Score (DAS 28), and US-PD assessment. US-PD findings were scored according to a semiquantitative scale (ranging 0-3) for synovial proliferation (SP), joint effusion (SE), bone erosions (BE), and PD.
Results:
Data obtained for clinical, laboratory findings and US-PD evaluation showed statistical significant improvement in all the measures performed except for BE. A significant parallel decrease in SE, SP, and PD values were demonstrated.
Conclusion:
This study demonstrated that US-PD is a valid technique in monitoring the response to adalimumab in moderate-to-severe PsA.
