Histological, immunohistological, and clinical features of merkel cell carcinoma in correlation to merkel cell polyomavirus status
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Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
1Department of Dermatology and Allergy Biederstein, Technische Universität München, 80802 Munich, Germany.
Journal of Skin Cancer
|June 1, 2012
Abstract:
Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lymphoma and atypical fibroxanthoma. In this review article clinical, histopathological and immunhistochemical features of Merkel cell carcinoma are reported. In addition, the role of Merkel cell polyomavirus is discussed.

