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Massive histamine release in a patient with systemic mastocytosis
J P Desborough1, I Taylor, A Hattersley
1Department of Anesthestic, Royal Postgraduate Medical School, Hammersmith Hospital, London.
British Journal of Anaesthesia
|December 1, 1990
Abstract:
We have measured plasma histamine concentrations, systemic vascular resistance, cardiac output and arterial pressure during laparotomy in a patient with systemic mastocytosis. The patient developed vasodilation and hypotension during surgery, associated with a massive increase in plasma histamine concentration.