Related Experiment Video
Updated: May 21, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Access-site complications and their management during transradial cardiac catheterization
Tariq Bhat1, Sumaya Teli, Hilal Bhat
1Department of Medicine, Staten Island University Hospital, 475 Seaview Avenue, Staten Island, NY 10305, USA. mohiuddin_bhat@yahoo.com
Insights
Transradial access for cardiac catheterization offers reduced complications but requires awareness of potential issues like radial artery spasm. Vigilant monitoring and proper technique are crucial for preventing serious complications and ensuring patient safety.
Area of Science:
- Cardiology
- Vascular Access Techniques
Background:
- Transradial access (TRA) is a preferred method for cardiac catheterization due to lower complication rates than transfemoral access.
- Increasing adoption of TRA necessitates a comprehensive understanding of its associated complications.
Purpose of the Study:
- To review and highlight the spectrum of complications associated with transradial access.
- To emphasize the importance of prevention and timely management of these complications.
Main Methods:
- Review of literature and clinical experience regarding transradial access complications.
- Categorization of complications based on frequency and severity.
Main Results:
- Common complications include asymptomatic radial artery occlusion, nonocclusive injury, and spasm.
- Rare complications include symptomatic occlusion, pseudoaneurysm, and perforation.
- Very rare complications include arteriovenous fistula, nerve damage, and complex regional pain syndrome.
Conclusions:
- While TRA is safe, awareness of potential complications like radial artery spasm is critical.
- Minimizing complications involves proper technique, sheath selection, anticoagulation, and post-procedure monitoring.
- Early recognition and management are key to preventing severe outcomes such as hand ischemia.
Abstract:
Transradial access for cardiac catheterization is now widely accepted among the invasive cardiology community as a safe and viable approach with a markedly reduced incidence of major access-related complications compared with the transfemoral approach. As this access technique is now being used more commonly for cardiac catheterization, it is of paramount importance to be aware of its complications and to understand their prevention and management. Some of the common complications of transradial access include asymptomatic radial artery occlusion, nonocclusive radial artery injury and radial artery spasm. Among these complications, radial artery spasm is still a significant challenge. Symptomatic radial arterial occlusion, pseudoaneurysm and radial artery perforation are rarely reported complications of the transradial approach. Early identification of these rare complications and their immediate management is of vital importance. Arteriovenous fistula, minor nerve damage and complex regional pain syndrome are very rare but have been reported. Recently, granulomas have been reported to be associated with the use of a particular brand of hydrophilic sheaths during the procedure. Generally, access-site complications can be minimized by avoiding multiple punctures, selection of smaller sheaths, gentle catheter manipulation, adequate anticoagulation, use of appropriate compression devices and avoiding prolonged high-pressure compression. In addition, careful observation for any ominous signs such as pain, numbness and hematoma formation during and in the immediate postprocedure period is essential in the prevention of catastrophic hand ischemia.
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