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Factors associated with bowel resection among infants with intussusception in the United States

Brian Johnson1, Paul Gargiullo, Trudy V Murphy

  • 1Department of Emergency Medicine, Highland General Hospital, Oakland, CA, USA.

Pediatric Emergency Care
|June 2, 2012
PubMed

Insights

Infants with intussusception requiring bowel resection were more likely to have fever and prolonged symptoms. However, severe cases can occur without these indicators, necessitating careful evaluation.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Clinical Pediatrics

Background:

  • Intussusception is the primary cause of bowel obstruction in infants.
  • Timely diagnosis is crucial to prevent severe complications.

Purpose of the Study:

  • To identify factors predicting the need for bowel resection in intussusception cases.
  • To analyze data from a large national study on intussusception and Rotashield.

Main Methods:

  • Examined 376 intussusception cases unrelated to Rotashield.
  • Compared clinical characteristics of infants who underwent bowel resection versus those who did not.
  • Confirmed cases via radiology, surgery, or autopsy.

Main Results:

  • Fever on admission significantly increased the risk of bowel resection (OR, 2.7).
  • Symptoms lasting at least 2 days before admission independently predicted bowel resection (aOR, 2.7).
  • Bowel resection was required in 33% of surgically treated intussusception cases.

Conclusions:

  • Documented fever and prolonged symptoms (≥2 days) are associated with a higher likelihood of bowel resection in intussusception.
  • Severe intussusception requiring resection can occur even without fever or prolonged symptoms.
  • Clinical vigilance is essential for all intussusception cases, regardless of symptom duration or fever presence.
Abstract

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