[Diagnostic importance of laboratory indicators in persons with alcoholism]

We investigated the diagnostic significance (efficacy) of 15 laboratory parameters in a group of 147 males (69 practically healthy volunteers and 78 alcoholics). We found that determination of IgA is of the greatest diagnostic value. This is followed by activity of gamma-glutamyltranspeptidase and aspartate-transaminase, whilst IgG is in the fourth place and coeruloplasmin in the sixth place. Results of our study indicate that none of followed parameters can be suggested as the only marker of chronic alcohol intoxication. A way to enhancement of diagnostic significance of laboratory parameters may be application of multifactorial analysis with the use of a group of clinical and laboratory parameters.