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Bioorthogonal Chemical Imaging of Cell Metabolism Regulated by Aromatic Amino Acids
Published on: May 12, 2023
Reaction-based two-photon probes for in vitro analysis and cellular imaging of monoamine oxidase activity
Dokyoung Kim1, Sunderraman Sambasivan, Hyoseok Nam
1Department of Chemistry, Center for Electro-Photo Behaviors in Advanced Molecular Systems, POSTECH, San 31, Hyoja-dong, Pohang, 790-784, Republic of Korea.
Chemical Communications (Cambridge, England)
|June 2, 2012
Abstract:
Reaction-based fluorescent probes for monoamine oxidases A and B are developed based on a new two-photon absorbing compound and its precursor. The probes show turn-on fluorescence response to the enzymes owing to the two-photon absorbing compound produced by the enzymatic activity, as monitored by one- as well as two-photon microscopy for the first time.
