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Iron overload and toxicity: implications for anesthesiologists
Aryeh Shander1, Ulrike Berth, Joanne Betta
1Department of Anesthesiology, Critical Care and Hyperbaric Medicine, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA. Aryeh.shander@ehmc.com
Abstract:
Conditions leading to iron overload range from rare hereditary disorders to more common medical conditions associated with chronic blood transfusions. Iron overload has deleterious effects on various vital organs (eg, liver, heart, and endocrine glands). Serum ferritin (in conjunction with transferrin saturation) is the most widely used test to evaluate iron burden and to screen for iron overload. The management plan should be adjusted to account for iron overload and potential consequences of liver, heart, and other organ involvement.
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