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[Stereotactic radiotherapy in pediatric indications]
V Bernier-Chastagner1, S Supiot, C Carrie
1Département de radiothérapie, centre Alexis-Vautrin, avenue de Bourgogne, Vandœuvre-lès-Nancy cedex, France. v.bernier@nancy.fnclcc.fr
Summary
Stereotactic radiotherapy, a high-precision technique, is expanding beyond brain treatments to new sites. In pediatrics, its use is cautious due to potential long-term side effects requiring careful consideration.
Area of Science:
- Radiation oncology
- Medical physics
- Pediatric oncology
Context:
- Stereotactic radiotherapy (SRT) has evolved from a niche radiosurgery technique to a broader application.
- Technological advancements have enabled SRT for extracerebral locations, expanding its utility.
- Pediatric applications of SRT are currently limited due to concerns about long-term late effects.
Purpose:
- To review the current state of stereotactic radiotherapy in pediatric patients.
- To discuss technical evolutions and specific indications for pediatric SRT.
- To highlight differences between pediatric and adult SRT applications and outline future research directions.
Summary:
- This review examines the evolving landscape of stereotactic radiotherapy, detailing its technical advancements and expanding applications.
- It focuses on the current validated pediatric indications for SRT, contrasting them with adult treatments.
- The review emphasizes the need to address potential long-term side effects in pediatric patients, influencing its cautious application.
Impact:
- Provides a comprehensive overview of pediatric stereotactic radiotherapy for clinicians and researchers.
- Highlights key considerations and challenges in applying SRT to pediatric populations.
- Informs future research and clinical practice guidelines for pediatric SRT.
