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Related Concept Videos

Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Related Experiment Video

Updated: May 21, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
09:15

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine

Published on: February 24, 2023

Cancer therapy and vaccination.

Hamdy A A Aly1

  • 1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt. hamdyaali@yahoo.com

Journal of Immunological Methods
|June 5, 2012
PubMed
Summary

Cancer vaccines offer a targeted immunotherapy approach, generating specific immune responses against tumors. This method aims for high efficacy with minimal impact on healthy cells, potentially preventing recurrence.

Area of Science:

  • Oncology
  • Immunology
  • Vaccinology

Background:

  • Cancer is a leading global cause of death, affecting all ages, with incidence increasing with age.
  • Current treatments like surgery, chemotherapy, and radiotherapy lack tumor specificity, causing adverse side effects.
  • The ideal cancer therapy targets tumor cells specifically, minimizing harm to normal cells.

Purpose of the Study:

  • To explore cancer vaccines as a specific and effective immunotherapy.
  • To highlight the potential of cancer vaccines in preventing and treating cancer.
  • To discuss various vaccine compositions and their mechanisms.

Main Methods:

  • Review of current cancer vaccine strategies and compositions.
  • Discussion of tumor-associated antigens (TAAs) and tumor-specific antigens (TSAs).

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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

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Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells
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Analysis of Human T Cell Activity in an Allogeneic Co-Culture Setting of Pre-Treated Tumor Cells

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Last Updated: May 21, 2026

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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  • Exploration of vaccine platforms including whole cells, dendritic cells, peptides, and DNA.

    • Main Results:

    • Cancer vaccines induce tumor-specific immune responses.
    • Vaccines offer specificity for tumor cells and long-lasting immunological memory.
    • Various vaccine formulations aim to elicit targeted antitumor immunity.

    Conclusions:

    • Cancer vaccines represent a promising, specific immunotherapy with potential for long-term protection.
    • Targeting TAAs and TSAs is crucial for developing effective cancer vaccination strategies.
    • Diverse vaccine platforms are being developed to achieve precise antitumor immune responses.