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Updated: May 21, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Risk factors associated with ischemic heart disease occurence in acute ischemic stroke patients
Michal Kovacik1, Stefan Madarasz, Michal Kral
1Comprehensive Stroke Centre, Department of Neurology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech Republic. michal22kovacik@gmail.com
Insights
Age and arterial hypertension are key risk factors for ischemic heart disease (IHD) in patients who have had an ischemic stroke (IS). Identifying these factors aids in stratifying IS patients for IHD detection and management.
Area of Science:
- Cardiology
- Neurology
- Public Health
Background:
- Ischemic heart disease (IHD) poses a significant mortality risk for ischemic stroke (IS) patients.
- Not all IS patients receive IHD screening.
- Identifying specific risk factors for IHD in IS patients is crucial for risk stratification.
Purpose of the Study:
- To identify exclusive risk factors (RFs) associated with IHD occurrence in IS patients.
- To aid in stratifying IS patients for IHD detection.
Main Methods:
- Retrospective, single-center study of 192 IS patients.
- Patients divided into two subgroups: with and without IHD.
- Logistic regression analysis used to evaluate risk factors including age, sex, arterial hypertension, atrial fibrillation, diabetes mellitus, lipid profiles, BMI, and carotid plaques.
Main Results:
- Age (OR=1.109) and arterial hypertension (OR=6.298) were exclusively and significantly associated with IHD in IS patients.
- P-values for age and arterial hypertension were P=0.001 and P=0.003, respectively.
Conclusions:
- Age and arterial hypertension are identified as exclusive risk factors for IHD in IS patients.
- These findings can guide IHD screening and management strategies for IS survivors.
Aims:
At specific time periods following ischemic stroke (IS), acute coronary syndrome as ischemic heart disease (IHD) represents a higher risk of death than IS. Not all IS patients can undergo specific examination for IHD detection. The aim of this study was to assess exclusive risk factors (RFs) associated with IHD occurrence in IS patients. Knowledge of these RFs should help in stratifying IS patients for IHD detection.
Materials And Methods:
This was a hospital-based, retrospective, single centre study. The sample consisted of 192 consecutive IS patients, divided into two subgroups - Subgroup 1 (54 patients without IHD; 55.6% males; 63.1 ± 11.8 years) and Subgroup 2 (138 patients with IHD; 39.1% males; 76.3 ± 9.6 years). The following factors were identified: age; sex; presence of arterial hypertension, atrial fibrillation, diabetes mellitus; plasma levels of total cholesterol, triglycerides, low-density cholesterol, high-density cholesterol; body mass index; presence of carotid plaques. Logistic regression analysis was used for statistical evaluation.
Results:
Of all identified risk factors only age (OR=1.109; 95% CI: 1.069 - 1.150, P=0.001) and the presence of arterial hypertension (OR=6.298; 95% CI: 2.215 - 17.905, P=0.003) were exclusively and significantly associated with the presence of IHD in IS patients.
Conclusions:
Age and arterial hypertension may be exclusive risk factors associated with IHD in IS patients.
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