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Updated: May 21, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
ConoDictor: a tool for prediction of conopeptide superfamilies
Dominique Koua1, Age Brauer, Silja Laht
1Atheris Laboratories, Case postale 314, CH-1233 Bernex-Geneva, Switzerland. dominique.koua@atheris.ch
Abstract:
ConoDictor is a tool that enables fast and accurate classification of conopeptides into superfamilies based on their amino acid sequence. ConoDictor combines predictions from two complementary approaches-profile hidden Markov models and generalized profiles. Results appear in a browser as tables that can be downloaded in various formats. This application is particularly valuable in view of the exponentially increasing number of conopeptides that are being identified. ConoDictor was written in Perl using the common gateway interface module with a php submission page. Sequence matching is performed with hmmsearch from HMMER 3 and ps_scan.pl from the pftools 2.3 package. ConoDictor is freely accessible at http://conco.ebc.ee.
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