Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...

Hemodialysis III: Nursing Management

Hemodialysis III: Nursing Management

The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this measurement...

Aneurysm IV: Nursing Management

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the exudate's...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Autism and anaesthesia: a simple framework for everyday practice.

BJA education·2024

Same author

Systemic sclerosis. Part II: perioperative considerations.

BJA education·2023

Same author

Systemic sclerosis. Part I: epidemiology, diagnosis and therapy.

BJA education·2023

Same author

Avelumab in unresectable/metastatic, progressive, grade 2-3 neuroendocrine neoplasms (NENs): Combined results from NET-001 and NET-002 trials.

European journal of cancer (Oxford, England : 1990)·2022

Same author

Clustering of comorbidities and associated outcomes in people with osteoarthritis - A UK Clinical Practice Research Datalink study.

Osteoarthritis and cartilage·2022

Same author

Comparative efficacy and safety of acetaminophen, topical and oral non-steroidal anti-inflammatory drugs for knee osteoarthritis: evidence from a network meta-analysis of randomized controlled trials and real-world data.

Osteoarthritis and cartilage·2021

Search research articles

Related Experiment Video

Updated: May 21, 2026

Use of Cerebral Open-Flow Microperfusion for the Longitudinal Collection of Interstitial Fluid in an Animal Model of Glioblastoma

Use of Cerebral Open-Flow Microperfusion for the Longitudinal Collection of Interstitial Fluid in an Animal Model of Glioblastoma

Published on: December 23, 2025

Intraoperative fluids: how much is too much?

M Doherty¹, D J Buggy

¹Department of Anaesthesia, Mater Misericordiae University Hospital, University College Dublin, Ireland. margaretdoherty@yahoo.com

British Journal of Anaesthesia

|June 5, 2012

Summary

This summary is machine-generated.

Intraoperative fluid therapy significantly impacts surgical outcomes. Individualized goal-directed fluid therapy, guided by monitoring, improves patient recovery, contrasting with older, less precise methods.

More Related Videos

Ex Vivo Hepatic Perfusion Through the Portal Vein in Mouse

Ex Vivo Hepatic Perfusion Through the Portal Vein in Mouse

Published on: March 9, 2022

Related Experiment Videos

Last Updated: May 21, 2026

Use of Cerebral Open-Flow Microperfusion for the Longitudinal Collection of Interstitial Fluid in an Animal Model of Glioblastoma

Use of Cerebral Open-Flow Microperfusion for the Longitudinal Collection of Interstitial Fluid in an Animal Model of Glioblastoma

Published on: December 23, 2025

Ex Vivo Hepatic Perfusion Through the Portal Vein in Mouse

Ex Vivo Hepatic Perfusion Through the Portal Vein in Mouse

Published on: March 9, 2022

Area of Science:

Anesthesiology
Critical Care Medicine
Surgical Outcomes

Background:

Historically, large crystalloid volumes were given intraoperatively based on presumed dehydration and 'third space' losses.
Positive fluid balance and weight gain post-surgery are linked to increased morbidity.
Preoperative dehydration is now rare due to shorter fasting and oral fluid intake.

Purpose of the Study:

To review the physiology of fluid distribution and capillary-tissue dynamics.
To outline the rationale behind various intraoperative fluid regimens.
To summarize current evidence on fluid therapy, emphasizing goal-directed approaches.

Main Methods:

Review of existing literature on intraoperative fluid therapy.
Analysis of physiological principles of fluid balance.
Examination of clinical trial data for different fluid regimens.

Main Results:

Restrictive fluid regimens showed initial promise but yielded conflicting results due to inconsistent definitions.
Individualized goal-directed fluid therapy (GDFT) using esophageal Doppler monitoring improves outcomes, particularly in colorectal surgery.
High-volume crystalloid infusion benefits low-risk ambulatory surgery patients by reducing postoperative nausea, vomiting, dizziness, and pain.

Conclusions:

Intraoperative fluid management is critical for postoperative outcomes.
Individualized GDFT with advanced monitoring offers superior results compared to traditional methods.
Fluid therapy strategies must be tailored to surgical risk and patient population.