Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules

Formulation and Manufacturing Process: Physical Attributes of Generic Tablets and Capsules

Bioequivalence in generic drugs, such as tablets and capsules, refers to their pharmaceutical equivalence to the brand-name counterparts. However, for therapeutic equivalence, manufacturers must also consider physical attributes like size, shape, and weight (FDA Guidance for Industry, December 2003). Discrepancies in these aspects could impact patient compliance and cause medication errors. For instance, swallowing difficulties, often experienced with larger tablets or capsules, can lead to...

Manufacture of Concrete Masonry Units

Manufacture of Concrete Masonry Units

The process of manufacturing concrete masonry units begins by mixing stiff concrete composed of Portland cement, aggregates, and water. This mixture is then poured into metal molds. To ensure the concrete settles uniformly and to avoid separation of its components, the mixture in the molds is subjected to vibration. Shortly after, the still-wet blocks are removed from the molds and placed on racks.
These wet blocks are then transported for curing, which can occur in one of two environments: a...

Clinically Relevant Drug Product Specifications: Methods of Establishment

Clinically Relevant Drug Product Specifications: Methods of Establishment

Product specifications define the acceptable quality of a pharmaceutical product by ensuring identity, purity, potency, and strength. These specifications serve as benchmarks during development, manufacturing, and post-approval quality control. Clinically relevant specifications are particularly important because they directly relate to a drug's safety and efficacy in clinical use.Dissolution studies are critical biopharmaceutic tools that link in vitro behavior to in vivo performance. They...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Physicochemical characterization of an Iron based Indian traditional medicine: Mandura Bhasma.

Ancient science of life·2013

Same author

Nerve conduction study in healthy individuals: a preliminary age based study.

Kathmandu University medical journal (KUMJ)·2012

Same author

Vanga Bhasma and its XRD analysis.

Ancient science of life·2012

Same author

Critical study of the asavaishta preparations of brhatirayee.

Ancient science of life·2012

Same author

Evaluation of the effect of conventionally prepared swarna makshika bhasma on different bio-chemical parameters in experimental animals.

Journal of Ayurveda and integrative medicine·2012

Same author

Therapeutic uses of Swarnamakshika Bhasma (A Critical Review).

Ayu·2011

Search research articles

Related Experiment Video

Updated: May 21, 2026

Formation of Dispersible Taohong Siwu Tablets

Formation of Dispersible Taohong Siwu Tablets

Published on: February 3, 2023

Standard manufacturing procedure of Rajata Bhasma.

Rekha Chaturvedi¹, C B Jha

¹Lecturer, Department of Rasa Shastra, Vaidya Yagya Datta Sharma Ayurvedic College, Khurja, Bulandshahar, Uttar Pradesh, India.

|June 5, 2012

Summary

This study details standard manufacturing procedures (SMP) for Rajata Bhasma, an Ayurvedic metallic preparation. Utilizing a muffle furnace and mercury-sulfur medium enhances quality and therapeutic efficacy.

Keywords:

Bhavana Marana Rajata Rajata sindura Shodhana

More Related Videos

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

Related Experiment Videos

Last Updated: May 21, 2026

Formation of Dispersible Taohong Siwu Tablets

Formation of Dispersible Taohong Siwu Tablets

Published on: February 3, 2023

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

Area of Science:

Ayurvedic Medicine
Rasashastra
Pharmacology

Background:

Rasashastra, an Ayurvedic branch, focuses on mineral and metal processing for therapeutic benefits.
Rajata (silver) is a valuable metal used in Ayurvedic formulations, primarily as Bhasma.
Deterioration in Ayurvedic drug quality necessitates the development of Standard Manufacturing Procedures (SMP) for global acceptance.

Purpose of the Study:

To establish SMP for the preparation of Rajata Bhasma.
To investigate the impact of the Shodhana process on Rajata.
To optimize the manufacturing process for enhanced quality and reproducibility.

Main Methods:

Sourcing Rajata from the local market in Varanasi.
Preparation of Rajata Bhasma following classical guidelines.
Comparative analysis of Muffle Furnace versus conventional Puta methods.
Utilizing mercury and sulfur as processing mediums.

Main Results:

The Muffle Furnace offers superior temperature control compared to traditional Puta methods for Rajata Bhasma preparation.
The combination of mercury and sulfur proved to be an effective medium in the manufacturing process.
Standardized procedures are crucial for ensuring the safety, efficacy, and consistency of Ayurvedic metallic preparations.

Conclusions:

The developed SMP for Rajata Bhasma ensures quality, safety, and efficacy.
Modernized techniques like Muffle Furnace integration improve manufacturing consistency.
Standardized Ayurvedic medicines are essential for meeting global demand and ensuring therapeutic outcomes.