A Laplace pressure based microfluidic trap for passive droplet trapping and controlled release
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Updated: May 21, 2026

A Microfluidic-based Hydrodynamic Trap for Single Particles
Published on: January 21, 2011
Melinda G Simon1, Robert Lin, Jeffrey S Fisher
1Department of Biomedical Engineering, University of California, Irvine, 3201 Natural Sciences II, Irvine, California 92697, USA.
Abstract:
Here, we present a microfluidic droplet trap that takes advantage of the net Laplace pressure force generated when a droplet is differentially constricted. Mathematical simulations were first used to understand the working range of the component; followed by finite element modeling using the CFD software package to further characterize the behavior of the system. Controlled release of the trapped droplets is also demonstrated through both a mechanical method and a chemical method that manipulates the total pressure exerted on the trapped droplet. The unique design of this trapping device also provides the capability for selection of a single droplet from a train, as well as droplet fusion.

