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Spontaneous bacterial peritonitis due to Salmonella enteritidis in cirrhotic ascites
1Department of Internal Medicine, Hospital de Tarragona Joan XXIII, Spain.
Abstract:
Spontaneous bacterial peritonitis due to Salmonella is uncommon. We report three patients with ascites infected by Salmonella. All three patients had advanced chronic liver disease, typically cirrhosis with portal hypertension. Salmonella enteritidis grew in the ascite fluid culture of the three patients. There was no clinical or microbiological evidence of Salmonella infection other than in the ascitic fluid. One patient died before antibiotic treatment was started, but the other two were treated with different combinations of antimicrobial drugs. One of them died on the fourteenth day of hospitalization, and the other survived.
Insights
Spontaneous bacterial peritonitis from Salmonella is rare, especially in patients with advanced chronic liver disease. This case series highlights the challenges in diagnosing and treating Salmonella ascites infections, with a survival rate of one-third.
Area of Science:
- Hepatology
- Infectious Diseases
- Microbiology
Background:
- Spontaneous bacterial peritonitis (SBP) is a common complication in patients with advanced liver disease and ascites.
- Salmonella is an uncommon cause of SBP, with most cases linked to other sources of infection.
- Patients with cirrhosis and portal hypertension are at increased risk for SBP.