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Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
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Mycoplasma mastitis: causes, transmission, and control.

Lawrence K Fox1

  • 1Department of Veterinary Clinical Sciences, College of Veterinary Medicine, 100 Grimes Way, ADBF 2043, Washington State University, Pullman, WA 99164-7060, USA. fox@wsu.edu

The Veterinary Clinics of North America. Food Animal Practice
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Mycoplasma mastitis is an increasing concern in dairy herds, especially larger ones. Monitoring herd health and implementing biosecurity measures like quarantining new animals can help control its spread.

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Area of Science:

  • Veterinary Medicine
  • Animal Science
  • Infectious Diseases

Background:

  • Mycoplasma mastitis is an emerging pathogen in dairy cattle.
  • Increasing dairy herd size correlates with rising Mycoplasma mastitis prevalence.
  • Importation of cattle is a significant risk factor for introducing Mycoplasma infections.

Purpose of the Study:

  • To review the epidemiology and transmission of Mycoplasma mastitis.
  • To discuss biosecurity strategies for controlling Mycoplasma mastitis.
  • To highlight the importance of early detection and monitoring.

Main Methods:

  • Literature review of Mycoplasma mastitis transmission and control.
  • Analysis of the relationship between herd size and disease prevalence.
  • Discussion of biosecurity protocols including quarantine and hygiene.

Main Results:

  • Transmission occurs through direct contact with infected or colonized cattle.
  • Expanding herds and cattle importation increase Mycoplasma mastitis incidence.
  • Effective milking hygiene may reduce the need for strict quarantine in some cases.

Conclusions:

  • Quarantining new animals is a recommended biosecurity measure.
  • Excellent milking time hygiene is crucial for Mycoplasma mastitis control.
  • Bulk tank milk culturing is vital for early detection of Mycoplasma outbreaks.