Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Clinical Significance of Antibiotic Resistance

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...

Vaccinations

Vaccinations

Tonsillitis II: Management

Tonsillitis II: Management

This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity.

Healthcare Associated Infections II: Preventive Measures

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...

Vaccine Production

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...

Pneumonia V: Nursing management and Prevention

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Confirmed bacteriological diagnosis and cure of nonsevere gram-positive clinical mastitis cases enrolled in a randomized clinical trial based on results of on-farm culture.

JDS communications·2024

Same author

Herd management practices associated with bovine leukemia virus incidence rate in Michigan dairy farms.

Preventive veterinary medicine·2020

Same author

Short communication: Herd-level variables associated with overmilking in Michigan dairy herds.

Journal of dairy science·2019

Same author

Decreased milk yield is associated with delayed milk ejection.

Journal of dairy science·2019

Same author

Herd-level variables associated with premilking stimulation time in Michigan dairy herds.

Journal of dairy science·2019

Same author

Herd-level variables associated with delayed milk ejection in Michigan dairy herds.

Journal of dairy science·2018

Search research articles

Related Experiment Video

Updated: May 21, 2026

Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-κB Reporter Transgenic

Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-κB Reporter Transgenic

Published on: September 4, 2012

Vaccination strategies for mastitis.

R J Erskine¹

¹Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, D-202 Veterinary Teaching Hospital, East Lansing, MI 48824, USA. erskine@cvm.msu.edu

The Veterinary Clinics of North America. Food Animal Practice

|June 6, 2012

Summary

Dairy cows benefit from vaccination strategies against mastitis, particularly using J-5 bacterins. However, challenges remain in developing effective vaccines for chronic intramammary infections due to impaired immune function in the mammary gland.

More Related Videos

Bovine Mammary Gland Biopsy Techniques

Bovine Mammary Gland Biopsy Techniques

Published on: December 23, 2018

Related Experiment Videos

Last Updated: May 21, 2026

Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-κB Reporter Transgenic

Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-κB Reporter Transgenic

Published on: September 4, 2012

Bovine Mammary Gland Biopsy Techniques

Bovine Mammary Gland Biopsy Techniques

Published on: December 23, 2018

Area of Science:

Veterinary immunology
Dairy cattle health
Mastitis control

Background:

Gram-negative coliforms are a primary cause of mastitis in dairy herds.
Current vaccination strategies, like J-5 bacterins, are most effective against severe coliform mastitis.
Adapting immunization protocols to specific herd needs is crucial for success.

Purpose of the Study:

To evaluate the efficacy of existing vaccination strategies for mastitis control.
To identify challenges in developing vaccines for chronic intramammary infections (IMI).

Main Methods:

Review of current vaccination protocols, focusing on J-5 bacterins.
Analysis of the pathogenesis of coliform mastitis and immune response.
Assessment of challenges in vaccine development for chronic IMI.

Main Results:

J-5 bacterins are the most successful vaccination strategy currently available for dairy herd mastitis control.
The efficacy of J-5 bacterins may be linked to the systemic pathogenesis of severe coliform mastitis.
Developing vaccines for chronic IMI faces significant obstacles due to impaired mammary gland immune function and low milk antibody concentrations.

Conclusions:

Vaccination strategies, especially J-5 bacterins, are valuable tools in dairy herd mastitis control programs.
Further research is needed to overcome the challenges in developing effective vaccines against chronic intramammary pathogens.
Tailoring vaccination protocols to individual herd requirements is essential for optimal outcomes.