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Related Concept Videos

Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...
Spinal Cord01:26

Spinal Cord

The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
The Spinal Cord01:54

The Spinal Cord

The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...

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A Novel Vertebral Stabilization Method for Producing Contusive Spinal Cord Injury
09:24

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Published on: January 5, 2015

International spinal cord injury spinal column injury basic data set.

M F Dvorak1, P C Wing, M G Fehlings

  • 1Division of Spine, Department of Orthopaedics, University of British Columbia, Vancouver, British Columbia, Canada. marcel.dvorak@vch.ca

Spinal Cord
|June 6, 2012
PubMed
Summary
This summary is machine-generated.

A standardized data set for spinal column injuries was developed to improve data consistency in research. This International Spinal Cord Injury (SCI) Spinal Column Injury Basic Data Set aids global comparisons.

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Area of Science:

  • Spinal Cord Injury Research
  • Clinical Data Standardization
  • Traumatology

Background:

  • Spinal cord injury (SCI) research requires consistent data collection for accurate analysis.
  • Variability in data collection hinders comparisons across studies and institutions.
  • A need exists for a standardized data set for spinal column injuries.

Purpose of the Study:

  • To describe the development of the International Spinal Cord Injury (SCI) Spinal Column Injury Basic Data Set.
  • To establish a uniform method for collecting and reporting spinal column injury data.
  • To facilitate international collaboration and data sharing in SCI research.

Main Methods:

  • An international working group of experts was convened.
  • Data elements were selected, defined, and refined through expert consensus and feedback.
  • The data set underwent review and endorsement by key professional organizations, including ISCoS and ASIA.

Main Results:

  • The developed data set includes seven variables detailing the nature and extent of spinal column injuries.
  • Variables cover injury type, levels, and associated features, using alphanumeric coding and numeric scoring.
  • Specific variables address penetrating/blunt injury, injury levels, and traumatic translation.

Conclusions:

  • The International SCI Spinal Column Injury Basic Data Set enables standardized comparisons of spinal column injury data globally.
  • This data set supports the National Institute of Neurological Disorders and Stroke Common Data Element project.
  • Tools are available to aid investigators in implementing this data set in SCI clinical studies.