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The onset of a peripheral ameloblastoma

Kellen Cristine Tjioe1, José Humberto Damante, Denise Tostes Oliveira

  • 1Department of Stomatology, Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil.

Case Reports in Oncological Medicine
|June 6, 2012
PubMed

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...