Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Performance of left ventricle based on pressure-volume relation.

R M Shoucri1

  • 1Department of Mathematics and Computer Science, Royal Military College of Canada, Kingston, Ontario.

Journal of Biomedical Engineering
|November 1, 1990
PubMed
Summary

This study models left ventricular contraction to derive new equations for myocardial active force and pressure-volume relations. Findings suggest peak myocardial force occurs near end-systole, correlating with peak isovolumic pressure.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A non-invasive method to calculate parameters of non-linear end-systolic pressure-volume relation.

International journal of cardiology·2011
Same author

Fresnel zones calculation. Part 2.

Applied optics·2010
Same author

Application of the method of characteristics for the study of shock waves in models of blood flow in the aorta.

Cardiovascular engineering (Dordrecht, Netherlands)·2007
Same author

Active and passive stresses in the myocardium.

American journal of physiology. Heart and circulatory physiology·2000
Same author

Studying the mechanics of left ventricular contraction.

IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society·1998
Same author

Ventriculo-arterial coupling and the areas under the end-systolic pressure-volume relation.

Japanese heart journal·1997

Area of Science:

  • Cardiovascular Physiology
  • Biomechanical Engineering
  • Cardiac Mechanics

Background:

  • Understanding left ventricular mechanics is crucial for diagnosing and treating heart conditions.
  • Existing models may not fully capture the active force dynamics during cardiac contraction.

Purpose of the Study:

  • To derive an expression for radial active force in the myocardium using the body force concept.
  • To develop a novel equation for the pressure-volume relation within the Suga-Sagawa model.
  • To introduce new indices for quantifying left ventricular contraction mechanics.

Main Methods:

  • Utilized the concept of body force (force per unit volume) for analysis.
  • Modeled the left ventricle as a contracting, elastic, thick-walled cylinder.
  • Employed a quasi-static approximation, neglecting inertia forces.

Main Results:

  • Derived a novel equation for the pressure-volume relationship in the Suga-Sagawa model.
  • Demonstrated that peak myocardial radial active force occurs near end-systole.
  • Showed a relationship between peak active force and peak isovolumic pressure.

Conclusions:

  • The derived model provides new insights into left ventricular active force generation.
  • The findings enhance the understanding of the pressure-volume dynamics during cardiac contraction.
  • New mechanical indices offer quantitative measures for assessing ventricular function.

Related Experiment Videos