Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Cochlea01:13

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.
Perceiving Loudness, Pitch, and Location01:21

Perceiving Loudness, Pitch, and Location

The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimizing seed water content: relevance to storage stability and molecular mobility.

Journal of integrative plant biology·2010
Same author

Histone deacetylase inhibitor promotes differentiation of embryonic stem cells into neural cells in adherent monoculture.

Chinese medical journal·2010
Same author

Effects of simulated weightlessness on liver Hsp70 and Hsp70mRNA expression in rats.

International journal of clinical and experimental medicine·2010
Same author

5-HT modulation of pain in SI and SII revealed by fMRI.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences·2010
Same author

Control and characterization of the structural, electrical, and optical properties of amorphous zinc-indium-tin oxide thin films.

ACS applied materials & interfaces·2010
Same author

Serum thymidine kinase 1 correlates to clinical stages and clinical reactions and monitors the outcome of therapy of 1,247 cancer patients in routine clinical settings.

International journal of clinical oncology·2010

Related Experiment Video

Updated: May 21, 2026

Performing Intracochlear Electrocochleography During Cochlear Implantation
09:10

Performing Intracochlear Electrocochleography During Cochlear Implantation

Published on: March 8, 2022

High-frequency hearing impairment assessed with cochlear microphonics.

Ming Zhang1

  • 1Departments of Speech Pathology & Audiology and Surgery-Otolaryngology, University of Alberta and Glenrose Rehabilitation Hospital, Edmonton, Alberta, Canada. ming.zhang@ualberta.ca

Acta Oto-Laryngologica
|June 7, 2012
PubMed
Summary

Cochlear microphonic (CM) measurements show potential as a supplementary tool to otoacoustic emission (OAE) testing for evaluating low-frequency hearing. This study found CMs can be reliably measured in individuals with high-frequency hearing loss.

More Related Videos

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
06:04

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
09:54

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

Published on: May 10, 2019

Related Experiment Videos

Last Updated: May 21, 2026

Performing Intracochlear Electrocochleography During Cochlear Implantation
09:10

Performing Intracochlear Electrocochleography During Cochlear Implantation

Published on: March 8, 2022

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages
06:04

Systematic Hearing Performance Evaluation Process for Adolescents with Cochlear Implantation at Early Ages

Published on: March 24, 2023

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
09:54

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea

Published on: May 10, 2019

Area of Science:

  • Auditory Neuroscience
  • Otoacoustic Emissions
  • Electrocochleography

Background:

  • Otoacoustic emissions (OAEs) are used to assess cochlear function, but acoustic noise can interfere with low-frequency measurements.
  • Cochlear microphonics (CMs), measured via electrocochleography (ECochG), are also cochlear responses and may overcome OAE limitations.

Purpose of the Study:

  • To investigate the feasibility of measuring CMs in subjects with high-frequency hearing loss.
  • To compare CM measurements between individuals with high-frequency hearing loss and normal-hearing controls.
  • To explore CMs as a potential alternative or supplement to OAEs for low-frequency cochlear assessment.

Main Methods:

  • CMs were measured in human subjects using an ear canal electrode.
  • Distortion product OAEs (DPOAEs) and audiograms were used to characterize hearing loss.
  • CM waveforms were compared between a high-frequency hearing loss group and a normal-hearing control group.

Main Results:

  • Audiogram and DPOAE results confirmed accurate subject group selection.
  • Low-frequency CM waveforms (CMWs) were successfully measured in subjects with high-frequency hearing loss using ear canal electrodes.
  • CMW amplitudes showed no significant difference between groups at low frequencies but were significantly different at high frequencies.

Conclusions:

  • CM measurements are feasible in individuals with high-frequency hearing loss.
  • CMs may serve as a valuable supplementary method to OAEs for assessing low-frequency cochlear function in clinical settings.
  • This technique offers a potential solution to the limitations posed by acoustic noise in OAE measurements.