Related Experiment Video
Updated: May 21, 2026

Methodology for Sputum Induction and Laboratory Processing
Published on: December 17, 2017
The microbiology of asthma
Michael R Edwards1, Nathan W Bartlett, Tracy Hussell
1National Heart and Lung Institute, Centre for Respiratory Infection and MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London W2 1PG, UK. michael.edwards@ imperial.ac.uk
None:
Asthma remains an important human disease that is responsible for substantial worldwide morbidity and mortality. The causes of asthma are multifactorial and include a complex mix of environmental, immunological and host genetic factors. In addition, epidemiological studies show strong associations between asthma and infection with respiratory pathogens, including common respiratory viruses such as rhinoviruses, human respiratory syncytial virus, adenoviruses, coronaviruses and influenza viruses, as well as bacteria (including atypical bacteria) and fungi. In this Review, we describe the many roles of microorganisms in the risk of developing asthma and in the pathogenesis of and protection against the disease, and we discuss the mechanisms by which infections affect the severity and prevalence of asthma.
Related Concept Videos
Microbiota of the Respiratory Tract
Asthma I: Introduction
Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma-I: Introduction
Asthma III: Clinical Manifestations
