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Methapyrilene: DNA as a possible target
1Department of Environmental Health Sciences, Case Western Reserve University, Cleveland, OH 44106.
Mutation Research
|December 1, 1990
Abstract:
The structural features contributing to the potential carcinogenicity, DNA-reactivity and genotoxicity of methapyrilene and its non-carcinogenic congener pyrilamine were examined. The analyses suggest that the former has the potential for DNA-reactivity, a property which is absent from the latter.