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Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Neurocognitive alterations in hypertensive children and adolescents

Marc B Lande1, Juan C Kupferman, Heather R Adams

  • 1Department of Pediatrics, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA. marc_lande@urmc.rochester.edu

Journal of Clinical Hypertension (Greenwich, Conn.)
|June 8, 2012
PubMed

Insights

Children with hypertension show neurocognitive deficits and learning difficulties compared to healthy peers. Hypertension, especially with obesity, may increase risks for anxiety and depression in children.

Area of Science:

  • Pediatric Neurology
  • Neuropsychology
  • Cardiovascular Health

Background:

  • Adult hypertension is linked to cognitive deficits.
  • Emerging evidence suggests similar neurocognitive differences in hypertensive children.
  • Hypertension in children may impact learning and emotional well-being.

Purpose of the Study:

  • To review preliminary evidence of neurocognitive differences in children with hypertension.
  • To examine the association between childhood hypertension, obesity, and mental health.
  • To discuss findings on cerebrovascular reactivity in pediatric hypertension.

Main Methods:

  • Review of database and single-center studies.
  • Analysis of neuropsychological testing performance.
  • Examination of learning difficulties, depression, and anxiety prevalence.
  • Assessment of studies on cerebrovascular reactivity.

Main Results:

  • Children with hypertension exhibit neurocognitive deficits compared to normotensive controls.
  • Increased prevalence of learning difficulties is observed in hypertensive children.
  • Hypertension with obesity is associated with higher risks of depression and anxiety.
  • Preliminary data suggest blunted cerebrovascular reactivity in hypertensive children.

Conclusions:

  • Hypertension in children is associated with significant neurocognitive impairments.
  • Early identification and management of hypertension in children are crucial for cognitive and emotional health.
  • Further research is needed to understand the long-term impact of pediatric hypertension on brain health.

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