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Updated: May 21, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
Published on: December 7, 2021
Analysis of population structure among Korean and Japanese Legionella pneumophila isolates using hsp60 sequences
Chan Geun Park1, Byoung Jun Kim, Hee-Youn Kim
1Department of Microbiology and Institute of Endemic Diseases, Seoul National University College of Medicine (SNUMRC), Seoul National University Hospital, Seoul, Korea.
Abstract:
The population structure of Korean (150 strains) and Japanese (92 strains) Legionella pneumophila isolates along with 18 reference strains were investigated using hsp60 sequence (1647 bp) analysis. Twelve clonal subgroups (hsP-I to hsP-X and hsF-I and hsF-II) were designated on the hsp60 tree, inferred from representative sequences using the neighbor-joining method. Some of the isolates showed unique subgroups depending on the source of isolates, including hsP-I, hsF-I, and hsF-II from cooling tower water, and subgroups hsP-VIII and hsP-X from circulating hot water bath. These subgroups may be useful for epidemiological studies to chase or specify sources of infection in Korea and Japan.
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