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The relationship between objectively measured physical activity, sedentary time, and vascular health in children
Lindsay Nettlefold1, Heather A McKay, Patti-Jean Naylor
1Centre for Hip Health and Mobility, Vancouver Coastal Health Research Institute, Vancouver, British Columbia, Canada.
Insights
Physical activity is linked to small artery compliance in children, but not large artery compliance. Further research is needed on activity bout frequency and interventions to improve arterial health.
Area of Science:
- Pediatric cardiology
- Vascular physiology
- Exercise science
Background:
- Physical activity (PA) benefits arterial compliance in adults.
- The association between PA and arterial compliance in children remains unclear.
- This study investigates PA and sedentary time's impact on children's arterial compliance.
Purpose of the Study:
- To examine the cross-sectional relationship between physical activity and sedentary time with arterial compliance in children.
- To determine if bouted moderate-to-vigorous physical activity (MVPA) is associated with arterial compliance independently of total MVPA.
Main Methods:
- Arterial compliance (large and small arteries) measured by diastolic pulse contour analysis in 102 children (8-11 years).
- Activity classified using accelerometers: sedentary, light, or moderate-to-vigorous physical activity (MVPA).
- Hierarchical linear regression analyzed activity's contribution to arterial compliance, controlling for BMI, systolic blood pressure, and body surface area.
Main Results:
- Physical activity variables did not significantly explain variance in large artery compliance.
- Light activity and MVPA explained additional variance in small artery compliance (5.8% and 2.7%, respectively).
- Bout duration of MVPA was not significantly associated with small artery compliance after accounting for total MVPA.
Conclusions:
- Objectively measured physical activity is associated with small artery compliance, but not large artery compliance, in children aged 8-11.
- Future research should investigate the influence of physical activity bout frequency.
- The impact of physical activity interventions on pediatric arterial compliance warrants further exploration.
Background:
Physical activity (PA) is beneficially associated with arterial compliance in adults; however, whether this association persists in children is unclear. We examined the cross-sectional relationship of PA and sedentary time with arterial compliance in children.
Methods:
Large and small artery compliance was determined by diastolic pulse contour analysis in 102 children aged 8-11 years (43 boys). We used accelerometers and age-specific cut points to classify activity as sedentary, light, or moderate-to-vigorous (MVPA). We also categorized MVPA according to bout length (0-5, 5-10, 10-20, and ≥20 min). Hierarchical linear regression examined: (i) the contribution of activity to large and small artery compliance (controlling for body surface area, systolic blood pressure, and body mass index (BMI)) and (ii) whether bouted MVPA was associated with arterial compliance independent of total MVPA.
Results:
Activity variables did not explain any additional variance in large artery compliance beyond that captured by body surface area, BMI, and systolic blood pressure (P = 0.118 to P = 0.990). Light activity and MVPA explained an additional 5.8% (P = 0.003) and 2.7% (P = 0.043) of the variance in small artery compliance. MVPA accumulated in bouts was not significantly associated with small artery compliance after controlling for the total volume of MVPA (P = 0.784 to P = 0.923).
Conclusions:
Objectively measured PA is associated with small, but not large artery compliance in children aged 8-11 years. Future research should explore the influence of bout frequency and the effect of a PA.intervention on arterial compliance.
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