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Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

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Related Experiment Video

Updated: May 21, 2026

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Donor Posterior Atrial Flap Rotation for Left Atrial Cuff Reconstruction in Lung Transplantation

Published on: October 11, 2024

[Primary graft dysfunction after lung transplantation].

V J Suárez López¹, E Miñambres, J C Robles Arista

¹Servicio Medicina Intensiva, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, España.

Medicina Intensiva

|June 8, 2012

Summary

This summary is machine-generated.

Primary graft dysfunction (PGD) is a severe lung injury after lung transplantation, causing high mortality. Research aims to identify risk factors and develop treatments for this critical complication.

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Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Published on: July 10, 2012

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Last Updated: May 21, 2026

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Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation

Published on: July 10, 2012

Area of Science:

Pulmonology
Transplant Surgery
Critical Care Medicine

Context:

Lung transplantation is a life-saving procedure for end-stage lung diseases.
Primary graft dysfunction (PGD) is a significant post-transplant complication.
PGD presents as acute lung injury in the early postoperative period.

Purpose:

To define and clarify primary graft dysfunction (PGD).
To identify risk factors and understand the pathophysiology of PGD.
To explore potential therapeutic strategies for PGD.

Summary:

Primary graft dysfunction (PGD) is defined as non-cardiogenic pulmonary edema within 72 hours post-reperfusion, linked to lung parenchyma damage.
It is a major cause of morbidity and mortality following lung transplantation.
Studies investigate risk factors and underlying mechanisms to guide treatment.

Impact:

Improved understanding of PGD pathophysiology.
Potential for novel therapeutic interventions.
Reduced mortality and morbidity associated with lung transplantation.