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Longevity and the long arm of epigenetics: acquired parental marks influence lifespan across several generations
1University of Southern California, Davis School of Gerontology, Los Angeles, CA, USA.
Abstract:
A recent study reported that longevity in Caenorhabditits elegans can be inherited over several generations. This is probably achieved through the following epigenetic mechanism: inherited demethylated histones at some central loci, such as miRNA, transcription factors or signaling regulators affect the expression of certain genes leading to the longevity phenotype.
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