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Group-A-streptococcal meningitis in a 7-year-old child--a rare pathogen in a non-immune compromised patient

Leonarda Maria L M van Zitteren1, Niek L A Arents, Feico Halbertsma

  • 1Pediatrics Department, Máxima Medical Centre, Veldhoven, Netherlands.

BMJ Case Reports
|June 8, 2012
PubMed

Insights

Group A Streptococcus (GAS) meningitis is rare in children but carries high risks. Early diagnosis and treatment are crucial, with follow-up for developmental and hearing issues.

Area of Science:

  • Pediatric Infectious Diseases
  • Bacteriology
  • Neurology

Background:

  • Group A Streptococcus (GAS) is a rare cause of pediatric meningitis.
  • GAS meningitis is associated with significant morbidity (46%) and mortality (10%).

Observation:

  • A case of meningitis in a 7-year-old female child caused by GAS is presented.
  • GAS meningitis is often linked to ear-nose-throat (ENT) infections.

Findings:

  • Bacterial typification frequently identifies M-protein gene sequence type (EMM type) 1.0 in invasive GAS infections.
  • GAS is susceptible to empiric antibiotic therapies commonly used for meningitis.

Implications:

  • A thorough search for a GAS reservoir, particularly ENT infections, is recommended.
  • Post-treatment follow-up, including neurological and audiological assessments, is essential for affected children.

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