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M-type potassium channels modulate Schaffer collateral-CA1 glutamatergic synaptic transmission.

Jianli Sun1, Jaideep Kapur

  • 1Department of Neurology, Box 800394, University of Virginia-HSC, Charlottesville, VA 22908, USA.

The Journal of Physiology
|June 8, 2012
PubMed
Summary

M1 muscarinic receptor activation enhances glutamatergic transmission by inhibiting M-type potassium channels. This leads to increased presynaptic calcium influx and glutamate release in the hippocampus.

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