Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Nonconscious Mimicry

Nonconscious Mimicry

Nonconscious mimicry occurs when individuals alter their mannerisms to match the behaviors and expressions of those nearby, without intention.

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder

REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...

Facial Feedback Hypothesis

Facial Feedback Hypothesis

Charles Darwin proposed that facial expressions are an evolutionary adaptation for communication. He argued that these expressions are not influenced by culture but are universal across species. For example, a snarling expression with exposed teeth signals a threat in many animals, including humans. Darwin also suggested that displaying an emotion can intensify the feeling. Smiling, for example, could enhance one's sense of happiness. This idea laid the foundation for understanding the role of...

Magical Thinking

Magical Thinking

Magical thinking encompasses the belief in assumptions that defy logical reasoning yet appear intuitively convincing. It is a common psychological phenomenon that persists across various cultural and individual contexts. While these assumptions contradict empirical evidence and scientific laws, they often serve meaningful psychological roles in promoting emotional resilience and a sense of control, especially under stress or uncertainty.Thought-Action Fusion and the Law of SimilarityA key...

Behaviorism

Behaviorism

The field of behaviorism was pioneered by figures such as Ivan Pavlov, John B. Watson, and B.F. Skinner fundamentally shifted the focus of psychology to the observable and controllable aspects of human and animal behavior. This shift marked a critical evolution in the discipline, emphasizing scientific rigor and experimental methodology.
The core premise of behaviorism is its focus on observable behavior rather than internal thoughts or feelings. This approach argues that true scientific...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Asymptomatic hyperpigmented lesions on tongue.

Indian journal of dermatology, venereology and leprology·2022

Same author

Morphological variations of the condylar head among children aged 4-15 years: A panoramic study.

Journal of the Indian Society of Pedodontics and Preventive Dentistry·2022

Same author

Relationship between chronological age, dental age, and body height using Demirjian method among children aged 4-14 years in Pune - A radiographic study.

Journal of the Indian Society of Pedodontics and Preventive Dentistry·2021

Same author

Antibacterial effect of propolis derived from tribal region on <i>Streptococcus mutans</i> and <i>Lactobacillus acidophilus</i>: An <i>in vitro</i> study.

Journal of the Indian Society of Pedodontics and Preventive Dentistry·2018

Same author

<i>In vivo</i> Comparative Evaluation of Mineral Trioxide Aggregate and Formocresol Pulpotomy in Primary Molars: A 60-month Follow-up Study.

Contemporary clinical dentistry·2017

Same author

Assessment of the changes in the stress-related salivary cortisol levels to the various dental procedures in children.

Journal of the Indian Society of Pedodontics and Preventive Dentistry·2015

Search research articles

Related Experiment Video

Updated: May 21, 2026

Application of Passive Head Motion to Generate Defined Accelerations at the Heads of Rodents

Application of Passive Head Motion to Generate Defined Accelerations at the Heads of Rodents

Published on: July 21, 2022

Happy Puppet syndrome.

Priyanka Airen Sarkar¹, Anand Shigli, Chetan Patidar

¹Department of Pediatric Dentistry, Modern Dental College and Research Centre, Indore, India. priyankairen@gmail.com

BMJ Case Reports

|June 8, 2012

Summary

Angelman syndrome (AS), a neuro-genetic disorder, involves chromosome 15 deficits causing developmental delays and unique behaviors. A case study highlights a girl with AS diagnosed via chromosomal analysis revealing a 15q microdeletion.

Area of Science:

Genetics
Neurodevelopmental Disorders
Chromosomal Abnormalities

Background:

Angelman syndrome (AS) is a rare neuro-genetic disorder.
It is characterized by a partial deficit of paired autosomal chromosome 15.
AS presents with intellectual and developmental delays, seizures, sleep disturbances, and distinctive behavioral features.

Observation:

A 6.5-year-old girl exhibited clinical signs suggestive of AS at age 4.
Symptoms included mental retardation, epilepsy, absence of speech, gait impairment, and unprovoked laughter.
These clinical observations prompted further genetic investigation.

Findings:

Fluorescent in situ hybridization (FISH) analysis was performed.
The analysis revealed a microdeletion on the maternally derived allele of chromosome 15q.

More Related Videos

Pentylenetetrazole-Induced Kindling Mouse Model

Pentylenetetrazole-Induced Kindling Mouse Model

Published on: June 12, 2018

Related Experiment Videos

Last Updated: May 21, 2026

Application of Passive Head Motion to Generate Defined Accelerations at the Heads of Rodents

Application of Passive Head Motion to Generate Defined Accelerations at the Heads of Rodents

Published on: July 21, 2022

Pentylenetetrazole-Induced Kindling Mouse Model

Pentylenetetrazole-Induced Kindling Mouse Model

Published on: June 12, 2018

This finding confirms the genetic basis of AS in the presented case.

Implications:

This case reinforces the diagnostic utility of chromosomal analysis in AS.
Understanding the genetic underpinnings of AS is crucial for early diagnosis and management.
Further research into 15q microdeletions can improve therapeutic strategies for neuro-genetic disorders.