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Related Experiment Video

Updated: May 21, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

[Drug-resistant headache: is it the end?].

Bernard Nater¹, Catherine Dozier

¹Service de neurologie, Département des neurosciences cliniques, CHUV, 101 I Lausanne et 2, chemin des Croix-Rouges, 1007 Lausanne. bernardnater@bluewin.ch

Revue Medicale Suisse

|June 9, 2012

Summary

New treatments offer hope for chronic headache sufferers. Occipital nerve stimulation and botulinum toxin show promise for intractable cluster headache and migraine, improving quality of life.

Area of Science:

Neurology
Pain Medicine
Neurosurgery

Context:

Chronic primary headaches, including cluster headache and migraine, significantly impair daily function and quality of life.
Existing acute and preventive medications are often insufficient for managing severe, intractable headache conditions.

Purpose:

To review emerging therapeutic strategies for pharmacologically intractable chronic cluster headache and migraine.
To highlight the potential of novel treatments in managing debilitating headache disorders.

Summary:

Occipital nerve stimulation is emerging as a promising therapy for chronic cluster headache.
Botulinum toxin injections represent a significant advancement in the treatment of chronic migraine.
These interventions offer new hope for patients with headache conditions refractory to conventional treatments.

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Last Updated: May 21, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

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Published on: June 2, 2014

Investigating Migraine-Like Behavior Using Light Aversion in Mice

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Published on: August 11, 2021

Dural Stimulation and Periorbital von Frey Testing in Mice As a Preclinical Model of Headache

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Published on: July 29, 2021

Impact:

Potential to improve treatment outcomes for patients with severe, chronic headache disorders.
May reduce the functional interference and enhance the quality of life for individuals suffering from intractable migraines and cluster headaches.
Advances in neuromodulation and targeted pharmacotherapy are expanding the therapeutic landscape for headache management.