Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Performing a Simple Data Analysis using MS-Excel Function

Performing a Simple Data Analysis using MS-Excel Function

Microsoft Excel offers a suite of functions and tools ideal for statistical analysis, making it accessible to students and researchers. This article outlines fundamental Excel functions pivotal for data analysis.
SUM: This function calculates the total sum of a range of values. It's the foundation for aggregating data, essential for determining overall trends and totals in datasets.
AVERAGE: It computes the mean value of a given set of numbers, providing a quick insight into the central...

Fixing Double-strand Breaks

Fixing Double-strand Breaks

The double-stranded structure of DNA has two major advantages. First, it serves as a safe repository of genetic information where one strand serves as the back-up in case the other strand is damaged. Second, the double-helical structure can be wrapped around proteins called histones to form nucleosomes, which can then be tightly wound to form chromosomes. This way, DNA chains up to 2 inches long can be contained within microscopic structures in a cell. A double-stranded break not only damages...

Fixing Double-strand Breaks

Fixing Double-strand Breaks

The double-stranded structure of DNA has two major advantages. First, it serves as a safe repository of genetic information where one strand serves as the back-up in case the other strand is damaged. Second, the double-helical structure can be wrapped around proteins called histones to form nucleosomes, which can then be tightly wound to form chromosomes. This way, DNA chains up to 2 inches long can be contained within microscopic structures in a cell. A double-stranded break not only damages...

Overview of Microsoft Excel as a Data Analysis Tool

Overview of Microsoft Excel as a Data Analysis Tool

Microsoft Excel is a cornerstone tool for data analysis and statistical operations, offering a wide array of functionalities to manage, analyze, and visualize data efficiently. Recognized for its versatility, Excel facilitates the performance of basic to complex statistical operations, serving as an indispensable asset for analysts, researchers, and students alike. Excel's significance in data analysis emanates from its spreadsheet environment, where data can be organized in rows and columns,...

Microsoft Excel: Student's t-Test

Microsoft Excel: Student's t-Test

Student's t-test in Microsoft Excel is a statistical method used to compare the means of two groups to determine if they are significantly different from each other. It's commonly used to evaluate hypotheses, such as testing whether a treatment has an effect compared to a control group. Excel provides built-in functions to perform t-tests, making it accessible for users needing to conduct basic statistical analysis.
To conduct a t-test in Excel, use the T.TEST function or the "Data Analysis...

Sequences

Sequences

Sequences are fundamental mathematical objects consisting of ordered lists of numbers that follow a specific rule or pattern. Sequences are critical in various mathematical concepts, including calculus, series, and number theory. They can model real-world phenomena such as population growth, financial investments, and physical processes like the diminishing height of a bouncing ball.Each number in a sequence is referred to as a term. Typically, the terms are denoted as a1, a2, a3,…, where the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A phage repressor involved in the DNA-damage response of <i>Francisella</i>.

PNAS nexus·2026

Same author

Parallel regulatory circuits orchestrate biofilm formation in response to c-di-GMP levels and growth phase.

PLoS genetics·2025

Same author

Computational protocol for analyzing whole-genome sequencing data from Staphylococcus aureus clinical isolates.

STAR protocols·2025

Same author

Genomic analysis of <i>Staphylococcus aureus</i> isolates from bacteremia reveals genetic features associated with the COVID-19 pandemic.

iScience·2024

Same author

Complete genome and characteristics of cluster BC bacteriophage SoJo, isolated using <i>Streptomyces mirabilis</i> NRRL B-2400 in Columbia, MD.

Microbiology resource announcements·2024

Same author

Simultaneous entry as an adaptation to virulence in a novel satellite-helper system infecting Streptomyces species.

The ISME journal·2023

Search research articles

Related Experiment Video

Updated: May 21, 2026

An Analytical Tool-box for Comprehensive Biochemical, Structural and Transcriptome Evaluation of Oral Biofilms Mediated by Mutans Streptococci

An Analytical Tool-box for Comprehensive Biochemical, Structural and Transcriptome Evaluation of Oral Biofilms Mediated by Mutans Streptococci

Published on: January 25, 2011

BioWord: a sequence manipulation suite for Microsoft Word.

Laura J Anzaldi¹, Daniel Muñoz-Fernández, Ivan Erill

¹Department of Biological Sciences, University of Maryland Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.

BMC Bioinformatics

|June 9, 2012

Summary

BioWord is a new Microsoft Word template that integrates DNA and protein sequence manipulation tools. This bioinformatics software simplifies sequence analysis for biologists within a familiar interface.

More Related Videos

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Published on: December 13, 2024

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Related Experiment Videos

Last Updated: May 21, 2026

An Analytical Tool-box for Comprehensive Biochemical, Structural and Transcriptome Evaluation of Oral Biofilms Mediated by Mutans Streptococci

An Analytical Tool-box for Comprehensive Biochemical, Structural and Transcriptome Evaluation of Oral Biofilms Mediated by Mutans Streptococci

Published on: January 25, 2011

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Introductory Analysis and Validation of CUT&RUN Sequencing Data

Published on: December 13, 2024

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Using Phylogenetic Analysis to Investigate Eukaryotic Gene Origin

Published on: August 14, 2018

Area of Science:

Bioinformatics
Molecular Biology
Computational Biology

Background:

Biological sequence manipulation is crucial for biologists.
Current tools are fragmented across multiple programs and web servers, requiring frequent application switching.
This fragmentation complicates routine sequence analysis tasks.

Purpose of the Study:

To develop an integrated solution for DNA and protein sequence manipulation.
To provide biologists with a user-friendly tool within a familiar software environment.
To streamline the process of sequence analysis for researchers and students.

Main Methods:

Developed BioWord, a macro-enabled, self-installing Microsoft Word template.
Integrated a comprehensive suite of DNA and protein sequence manipulation tools.
Utilized Visual Basic for Applications (VBA) for an open-source, object-oriented design.

Main Results:

BioWord installs with a single click and appears as a tab in the Office ribbon.
Offers tools for sequence manipulation, dyad search, consensus logos, motif discovery, and pair-wise alignment.
Provides an open-source platform for user customization and expansion.

Conclusions:

BioWord consolidates powerful sequence analysis tools into a user-friendly interface.
Facilitates customization through a simple scripting language and object-oriented design.
Serves as an accessible educational platform for teaching bioinformatics algorithms.