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Updated: May 21, 2026

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
TRAIL as biomarker and potential therapeutic tool for cardiovascular diseases
Stella Bernardi1, Daniela Milani, Bruno Fabris
1Department of Morphology and Embriology, University of Ferrara, Via Fossato di Mortara 66, 44100 Ferrara, Italy.
Abstract:
This review focuses on TNF-related apoptosis-inducing ligand (TRAIL), also called Apo2 ligand, a protein belonging to the TNF superfamily. TRAIL can be found either in its transmembrane or circulating form, and its mostly studied peripheral effect is the induction of cellular apoptosis. Here, we discuss the evidences supporting the use of TRAIL as biomarker of cardiovascular diseases as well as the evidences showing the potential beneficial therapeutic effects of TRAIL on cardiovascular diseases and diabetes.
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