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[Side-effects of continuous and discontinuous cytapheresis]
E Fehérvízyová1, K Sviteková, M Hrubisko
1Klinika hematológie a transfuziológie FN Bratislava.
Vnitrni Lekarstvi
|November 1, 1990
Summary
Cytapheresis using automated cell separators is generally safe for blood donors. Continuous flow separators like the Fenwal CS 3000 showed fewer complications than discontinuous systems such as the Haemonetics model 30.
Area of Science:
- Hematology
- Medical Device Technology
Background:
- Cytapheresis is a common procedure for blood donation.
- Assessing complications is crucial for donor safety and procedure efficiency.
Purpose of the Study:
- To evaluate and compare the incidence of complications between two types of blood cell separators during cytapheresis.
- To identify common complications and discuss their prevention.
Main Methods:
- A retrospective analysis of 767 cytapheresis procedures.
- Comparison of complication rates between Haemonetics model 30 (discontinuous) and Fenwal CS 3000 (continuous) separators.
Main Results:
- Complication rates were significantly higher with the Haemonetics model 30 (27%) compared to the Fenwal CS 3000 (13.2%).
- Common complications included collapse and hypocalcemia symptoms.
- Serious adverse reactions were infrequent, occurring in 7.6% and 4.4% of cases, respectively.
Conclusions:
- Cytapheresis using automated separators is a safe donation method.
- Continuous flow separators appear to offer a lower complication profile for cytapheresis procedures.