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MRI for clinically suspected pediatric appendicitis: an implemented program
Michael M Moore1, Cristy N Gustas, Arabinda K Choudhary
1Department of Radiology, Penn State Milton S Hershey Medical Center, Hershey, PA 17033-0850, USA. mmoore5@hmc.psu.edu
Background:
Emergent MRI is now a viable alternative to CT for evaluating appendicitis while avoiding the detrimental effects of ionizing radiation. However, primary employment of MRI in the setting of clinically suspected pediatric appendicitis has remained significantly underutilized.
Objective:
To describe our institution's development and the results of a fully implemented clinical program using MRI as the primary imaging evaluation for children with suspected appendicitis.
Materials And Methods:
A four-sequence MRI protocol consisting of coronal and axial single-shot turbo spin-echo (SS-TSE) T2, coronal spectral adiabatic inversion recovery (SPAIR), and axial SS-TSE T2 with fat saturation was performed on 208 children, ages 3 to 17 years, with clinically suspected appendicitis. No intravenous or oral contrast material was administered. No sedation was administered. Data collection includes two separate areas: time parameter analysis and MRI diagnostic results.
Results:
Diagnostic accuracy of MRI for pediatric appendicitis indicated a sensitivity of 97.6% (CI: 87.1-99.9%), specificity 97.0% (CI: 93.2-99.0%), positive predictive value 88.9% (CI: 76.0-96.3%), and negative predictive value 99.4% (CI: 96.6-99.9%). Time parameter analysis indicated clinical feasibility, with time requested to first sequence obtained mean of 78.7 +/- 52.5 min, median 65 min; first-to-last sequence time stamp mean 14.2 +/- 8.8 min, median 12 min; last sequence to report mean 57.4 +/- 35.2 min, median 46 min. Mean age was 11.2 +/- 3.6 years old. Girls represented 57% of patients.
Conclusion:
MRI is an effective and efficient method of imaging children with clinically suspected appendicitis. Using an expedited four-sequence protocol, sensitivity and specificity are comparable to CT while avoiding the detrimental effects of ionizing radiation.
Insights
Magnetic Resonance Imaging (MRI) offers a safe and effective alternative to CT scans for diagnosing pediatric appendicitis. This study demonstrates MRI
Area of Science:
- Radiology
- Pediatric Imaging
- Emergency Medicine
Background:
- Emergent MRI is a viable alternative to CT for appendicitis evaluation, avoiding ionizing radiation.
- Pediatric appendicitis evaluation using MRI remains underutilized despite its benefits.
Purpose of the Study:
- To describe the development and outcomes of a clinical program utilizing MRI as the primary imaging modality for pediatric appendicitis.
- To assess the diagnostic accuracy and efficiency of an expedited MRI protocol in children.
Main Methods:
- A four-sequence MRI protocol was used for 208 children (ages 3-17) with suspected appendicitis.
- No intravenous/oral contrast or sedation was administered.
- Data collected included diagnostic results and time parameters.
Main Results:
- MRI demonstrated high diagnostic accuracy: 97.6% sensitivity and 97.0% specificity.
- The expedited protocol was clinically feasible, with efficient imaging and reporting times.
- Negative predictive value was 99.4%, indicating high confidence in ruling out appendicitis.
Conclusions:
- MRI is an effective and efficient imaging method for pediatric appendicitis.
- An expedited four-sequence MRI protocol achieves diagnostic performance comparable to CT.
- MRI provides a radiation-free imaging option for children with suspected appendicitis.
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