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Related Concept Videos

Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
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Abdominal Aorta

Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
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Arteries of Lower Limbs01:20

Arteries of Lower Limbs

The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular artery,...
Development of Blood Vessels01:07

Development of Blood Vessels

The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
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Abdominal Regions and Quadrants01:19

Abdominal Regions and Quadrants

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Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
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Published on: September 5, 2011

Single umbilical artery: Does side matter?

Mark Santillan1, Donna Santillan, Diedre Fleener

  • 1Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, IA, USA. mark-santillan@uiowa.edu

Fetal Diagnosis and Therapy
|June 9, 2012
PubMed
Summary
This summary is machine-generated.

A right-sided absent umbilical artery (AUA) in fetuses is linked to gastrointestinal and genitourinary abnormalities. This finding suggests right AUA may serve as an early marker for fetal anomalies.

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Published on: September 5, 2011

Area of Science:

  • Perinatal Medicine
  • Fetal Ultrasound
  • Congenital Abnormalities

Background:

  • An absent umbilical artery (AUA) is a rare condition.
  • The clinical significance of AUA laterality is not well-established.
  • Previous studies have not consistently linked AUA laterality to specific fetal defects.

Purpose of the Study:

  • To investigate the association between the laterality of an absent umbilical artery (AUA) and specific sonographic findings.
  • To determine if AUA laterality correlates with chromosomal defects or postpartum birth defects.
  • To assess the potential of AUA laterality as an early marker for fetal abnormalities.

Main Methods:

  • Retrospective cohort study of 405 patients with identified AUA laterality.
  • Review of ultrasound reports and medical records from 1989 to 2007.
  • Comparison of sonographic abnormalities between right and left AUA groups using Fisher's exact test and logistic regression.

Main Results:

  • Fetuses with a right AUA showed higher unadjusted rates of ultrasound abnormalities (51.1% vs. 37.0%).
  • A significantly higher percentage of isolated AUA was observed in the left AUA group (63.0% vs. 48.8%).
  • Multivariate analysis revealed a significant association between right AUA and fetal gastrointestinal (GI) and genitourinary (GU) abnormalities.

Conclusions:

  • A right AUA is significantly associated with concomitant fetal GI and GU abnormalities.
  • Laterality of the AUA can be an easily identified early marker for fetal anomalies.
  • This finding contrasts with previous reports and highlights the importance of assessing AUA laterality.