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Related Concept Videos

Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.

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Related Experiment Video

Updated: May 21, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

Molecular profiling for personalized cancer care.

Raheela Ashfaq1

  • 1Caris Life Sciences, 6655 North MacArthur Blvd., 3rd Floor, Irving, TX 75039, USA. rashfaq@carisls.com

Clinical & Experimental Metastasis
|June 9, 2012
PubMed
Summary

Genomic discoveries are revolutionizing cancer care, driving personalized therapies. Molecular profiling is essential for targeted cancer treatments with improved outcomes.

Area of Science:

  • Oncology
  • Genomics
  • Bioinformatics

Background:

  • Cancer research is rapidly advancing due to genomic discoveries.
  • Understanding cancer's biological dynamics is crucial for developing new therapies.
  • Current cancer care is shifting towards a personalized, biology-driven approach.

Purpose of the Study:

  • To highlight the impact of genomic discoveries on cancer diagnostics and therapeutics.
  • To emphasize the paradigm shift towards personalized cancer medicine.
  • To underscore the importance of molecular profiling in targeted therapy.

Main Methods:

  • Leveraging novel technologies and platforms for genomic analysis.
  • Utilizing bioinformatic tools for data interpretation.
  • Integrating molecular profiling into diagnostic and therapeutic strategies.

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Standardized SDS-PAGE Workflow for Personalized Protein Corona Profiling in Early Cancer Detection
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Standardized SDS-PAGE Workflow for Personalized Protein Corona Profiling in Early Cancer Detection

Published on: December 19, 2025

Related Experiment Videos

Last Updated: May 21, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
13:24

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Published on: April 11, 2016

Standardized SDS-PAGE Workflow for Personalized Protein Corona Profiling in Early Cancer Detection
10:02

Standardized SDS-PAGE Workflow for Personalized Protein Corona Profiling in Early Cancer Detection

Published on: December 19, 2025

Main Results:

  • Genomic insights are enabling the rational design of targeted cancer therapies.
  • Personalized medicine approaches are improving clinical outcomes and reducing morbidity.
  • Molecular profiling identifies specific genetic alterations for effective treatment.

Conclusions:

  • Genomic discoveries are transforming cancer care towards precision medicine.
  • Molecular profiling is a critical companion to targeted cancer therapies.
  • The future of cancer treatment lies in understanding tumor biology.