Related Experiment Video
Updated: Aug 5, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
Published on: December 2, 2015
[Life stress events preceding illness episodes in multiple sclerosis and ulcerative colitis--a comparison]
1Klinik und Poliklinik für Psychiatrie und Neurologie der Medizinischen Akademie, Carl Custav Carus, Dresden.
Abstract:
As to the prevention of somatic and psychosomatic diseases it should be tested, whether life-events are of interest to pathogenesis of disturbances like multiple sclerosis and ulcerative colitis. The social readjustment rating scale (Holmes, Rahe) was used and the life-change-unite-score of the groups of patients (n = 30) and a normal population was compared. Patients with m.s. and u.c. have a significant higher LCU-score than the normal group. Between the two diseases one can find no difference.
Related Concept Videos
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Introduction to Stress and Lifestyle
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease IV: Clinical Manifestations

