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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Disorders of Erythrocytes

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Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Accessory Structures of the Skin: Hair and Hair Follicles

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Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

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Published on: October 12, 2012

'Goose bumps'-associated anaemia.

Chisho Hoshino1, Akane Yamabe, Yoshiyuki Sekikawa

  • 1Department of General Internal Medicine, Ohta-Nishinouchi Hospital, Koriyama City, Fukushima, Japan. gim-hoshino@ohta-hp.or.jp

BMJ Case Reports
|June 9, 2012
PubMed
Summary

Helicobacter pylori infection can cause refractory iron-deficiency anaemia. Eradicating H. pylori resolved the patient's anaemia and improved iron absorption, highlighting its importance in unexplained cases.

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Area of Science:

  • Gastroenterology
  • Hematology

Background:

  • Iron-deficiency anaemia (IDA) is common but can be refractory to treatment.
  • Unexplained IDA requires investigation into underlying causes beyond typical gastrointestinal bleeding or menorrhagia.

Observation:

  • A 36-year-old woman presented with IDA refractory to iron supplementation.
  • Endoscopy revealed nodular gastritis ('Torihada-ien') associated with Helicobacter pylori (Hp) infection.
  • Stool occult blood and gynecologic evaluation were negative.

Findings:

  • Hp eradication therapy led to the resolution of anaemia.
  • The patient showed improved response to iron supplementation post-eradication.
  • This suggests Hp-associated gastritis as a cause of unexplained IDA.

Implications:

  • Helicobacter pylori-associated gastritis should be considered in patients with unexplained iron-deficiency anaemia.
  • This finding underscores the systemic impact of H. pylori infections.
  • Prompt diagnosis and treatment of Hp infection can resolve refractory IDA.