Related Experiment Video
Updated: May 21, 2026

In Vivo Functional Assessment of Rat Masseter Muscle Following Surgical Creation of a Volumetric Muscle Loss (VML) Injury
Published on: November 15, 2024
Masseter and medial pterygoid muscle hypertrophy
R Guruprasad1, Sudhirkumar Rishi, Preeti P Nair
1Department of Oral Medicine and Radiology, People's College of Dental Sciences & Research Centre, Bhopal, Madhya Pradesh, India.
Generalized masticatory muscle hypertrophy, specifically involving the masseter and medial pterygoid muscles, can be challenging to diagnose clinically. Advanced imaging like CT and MRI are crucial for accurate diagnosis when clinical examination is inconclusive.
Area of Science:
- * Anatomy and Physiology
- * Medical Imaging
- * Surgical Pathology
Background:
- * Hypertrophy is defined as an increase in cell size, not number, leading to tissue enlargement.
- * Generalized masticatory muscle hypertrophy can affect various muscles, including the temporalis, masseters, and medial pterygoids.
- * Masseteric hypertrophy often presents as painless swelling near the mandibular angle, posing a diagnostic challenge.
Observation:
- * Clinical presentation of masseteric hypertrophy can mimic parotid or dental conditions.
- * Differentiating benign hypertrophy from rare malignant muscle lesions solely on clinical examination is difficult.
- * A unique case involved combined masseter and medial pterygoid muscle hypertrophy.
Findings:
- * Clinical assessment alone failed to identify the extent of muscle hypertrophy.
- * Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) were essential for confirming the diagnosis.
- * The study highlights the diagnostic limitations of clinical examination in specific hypertrophy cases.
Implications:
- * Advanced imaging (CT/MRI) is vital for diagnosing complex masticatory muscle hypertrophy.
- * Accurate diagnosis prevents misidentification with other pathologies, ensuring appropriate patient management.
- * This case underscores the importance of advanced imaging in identifying rare anatomical variations and conditions.
Related Concept Videos
Muscles for Facial Expressions
Cellular Adaptation II: Hypertrophy
Muscles of the Anterior Neck
Muscles of the Eye
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and rotating...
Muscles that Move the Head
The bilateral sternocleidomastoid, or SCM, and the suprahyoid and infrahyoid muscles are significant head flexors. The SCM muscles originate at the sternum and clavicle and attach to the mastoid process of the temporal bone. The SCM contracts bilaterally to bend the head forward, whereas...

