Open-wound treatment for gunshot to the brain

Pepijn van den Munckhof1, Vincent G Geukers, Fonnet E Bleeker

  • 1Neurosurgical Center Amsterdam, Academic Medical Center, Room H2-241, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. p.vandenmunckhof@amc.uva.nl

Insights

A young girl with a brain gunshot wound survived after undergoing decompressive craniectomy and experimental open-wound treatment for elevated intracranial pressure. She achieved a good functional recovery, showcasing a novel treatment approach for severe traumatic brain injury.

Area of Science:

  • Pediatric neurosurgery
  • Trauma surgery
  • Emergency medicine

Background:

  • Gunshot wounds to the brain are rare and life-threatening injuries, particularly in young children.
  • Elevated intracranial pressure (ICP) is a critical complication that significantly increases mortality and morbidity.
  • Standard treatment protocols for pediatric traumatic brain injury (TBI) may require adaptation for complex penetrating injuries.

Observation:

  • A 2.5-year-old girl sustained a gunshot wound to the brain.
  • The patient presented with uncontrollably elevated intracranial pressure.
  • An emergent bilateral decompressive craniectomy was performed to manage the elevated ICP.

Findings:

  • The patient underwent an experimental open-wound treatment following the craniectomy.
  • The surgical intervention successfully reduced intracranial pressure.
  • The patient demonstrated a positive clinical response to the combined treatment approach.

Implications:

  • Bilateral decompressive craniectomy can be a life-saving procedure for pediatric TBI with refractory intracranial hypertension.
  • Experimental open-wound management may offer a viable option in select cases of severe TBI.
  • This case highlights the potential for good functional recovery even after devastating brain injuries with timely and aggressive intervention.

Related Concept Videos

Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...