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Updated: May 21, 2026

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
Published on: March 6, 2019
Methylsulfonyl benzothiazole (MSBT): a selective protein thiol blocking reagent
Dehui Zhang1, Nelmi O Devarie-Baez, Qian Li
1Department of Chemistry, Washington State University, Pullman, Washington 99164, USA.
Abstract:
A new thiol blocking reagent, methylsulfonyl benzothiazole, was discovered. This reagent showed good selectivity and high reactivity for protein thiols.
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