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Updated: May 21, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
Published on: July 29, 2014
[Locoregional analgesia in palliative care: a 4-year survey]
D Grouille1, B Sardin, G Terrier
1Service d'accompagnement et de soins palliatifs, pôle clinique médicale, CHU Dupuytren, 2, avenue Martin-Luther-King, 87042 Limoges cedex, France. dominique.grouille@chu-limoges.fr
Unlabelled:
It could append that patient pain relief in palliative care is not achieved despite the use of opioids and the multimodal approach. Therefore, regional techniques are used in the palliative care unit of the Limoges University Hospital since four years.
Patients And Methods:
From October 2006 to September 2010, every patient under regional technique was followed with a specific form. The items collected were demographic characteristics, underlying disease, and associated treatments. The efficacy of regional techniques on pain was scored.
Results:
Sixty-three patients, 39 males and 24 females, mean age 59 years, were treated by 104 regional procedures. There were 49 neuroaxial analgesia (40 spinal and nine epidural), 39 peripheral nerve blocks including 25 iliofascial blocks and 16 blocks for nerves of the scalp, face and neck. In 67.5% of the cases, the regional techniques provided adequate pain relief. For 24% of the cases, the results were uncompleted. Regional techniques were unsuccessful in 8.5%.
Conclusion:
Despite this underperformance in terms of pain control, a multicenter study is ongoing to evaluate the improvement of quality of life induced by the regional techniques.
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