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Related Concept Videos

Tracheostomy Care I: Pre-procedural Steps01:16

Tracheostomy Care I: Pre-procedural Steps

A tracheostomy is a surgical technique that involves making an incision in the neck to provide access to the trachea. It is frequently used in medical conditions such as airway obstruction and prolonged mechanical ventilation. Effective nursing management is crucial for the long-term success of a tracheostomy.
Required Equipment
The equipment necessary for tracheostomy care includes:
Tracheostomy: Procedure and Tubes01:28

Tracheostomy: Procedure and Tubes

A tracheostomy is a surgical procedure that creates an artificial opening into the trachea, typically at the second or third cartilaginous ring level. This opening allows the insertion of a tracheostomy tube, which can replace an endotracheal tube, provide mechanical ventilation, bypass an upper airway obstruction, or remove accumulated tracheobronchial secretions.
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Tracheostomy Decannulation01:21

Tracheostomy Decannulation

Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
Oxygen Delivering System III: Tracheostomy and T-piece01:23

Oxygen Delivering System III: Tracheostomy and T-piece

Oxygen delivery is critical in clinical care, especially for patients with respiratory disorders or those undergoing surgical procedures. Various systems, such as tracheostomy and the T-piece, deliver oxygen to the lungs, ensuring adequate arterial oxygenation.
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
Tracheostomy Care II: Procedure01:25

Tracheostomy Care II: Procedure

Tracheostomy care is an essential nursing skill that involves cleaning and maintaining a tracheostomy tube to prevent infection and other complications. Here's a step-by-step guide explaining each procedure with its rationale. Note that disposable gloves are to be worn at all times and changed as often as needed to maintain a sterile work environment, and to protect both patient and healthcare worker.
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask and...
Tracheostomy Suctioning I: Pre-Procedural Steps01:26

Tracheostomy Suctioning I: Pre-Procedural Steps

Tracheostomy suctioning is a critical procedure healthcare professionals perform to maintain a patent airway in patients with a tracheostomy tube. This procedure is necessary when secretions accumulate in the airway, causing respiratory distress. Here is a step-wise procedural guide for performing tracheostomy suctioning using an open system.
Equipment Required
First, gather all necessary equipment: a sterile suction catheter, a sterile disposable container, sterile gloves, a towel or...

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Related Experiment Video

Updated: May 21, 2026

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
06:15

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation

Published on: November 10, 2023

Learning curve in tracheal allotransplantation.

P R Delaere1, J J Vranckx, J Meulemans

  • 1Department of Otolaryngology Head & Neck Surgery, University Hospital Leuven, Belgium. pierre.delaere@uzleuven.be

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|June 12, 2012
PubMed
Summary

Vascularized tracheal allotransplantation shows promise, but recipient cell repopulation is crucial for long-term graft survival after immunosuppression withdrawal. Further research is needed to optimize this composite tissue allotransplantation approach.

More Related Videos

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
09:10

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Published on: January 20, 2010

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
09:57

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

Published on: April 1, 2019

Related Experiment Videos

Last Updated: May 21, 2026

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation
06:15

Murine Intrapulmonary Tracheal Transplantation: A Model for Investigating Obliterative Airway Disease After Lung Transplantation

Published on: November 10, 2023

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease
09:10

Heterotopic and Orthotopic Tracheal Transplantation in Mice used as Models to Study the Development of Obliterative Airway Disease

Published on: January 20, 2010

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model
09:57

Seeding and Implantation of a Biosynthetic Tissue-engineered Tracheal Graft in a Mouse Model

Published on: April 1, 2019

Area of Science:

  • Regenerative Medicine
  • Transplantation Immunology
  • Surgical Innovation

Background:

  • The first vascularized tracheal allotransplantation was performed in 2008, utilizing forearm implantation for revascularization.
  • Subsequent cases addressed long-segment tracheal stenosis and chondrosarcoma, aiming to shorten the interval to orthotopic transplantation and safely withdraw immunosuppression.

Observation:

  • All tracheal allografts achieved revascularization within two months following heterotopic forearm implantation.
  • Immunosuppression withdrawal was initiated four months post-implantation, completed within six weeks in three patients.
  • Mucosal lining repopulation by recipient cells was incomplete, leading to donor mucosa necrosis.

Findings:

  • Partial loss of the tracheal allograft occurred in three patients due to incomplete recipient cell repopulation.
  • One patient, who received additional measures for cell repopulation, experienced better outcomes.
  • The trachea can function as a composite tissue allotransplant after heterotopic revascularization.

Implications:

  • Maximizing recipient cell repopulation is critical for maintaining tracheal allograft viability after immunosuppression cessation.
  • This study highlights the potential of tracheal allotransplantation but underscores the challenges of achieving complete mucosal integration.
  • Further optimization of protocols is necessary to improve outcomes for composite tissue allotransplantation, particularly for airway reconstruction.